Impact of high-fructose diet and metformin on histomorphological and molecular parameters of reproductive organs and vaginal microbiota of female rat

Impact of high-fructose diet and metformin on histomorphological and molecular parameters of reproductive organs and vaginal microbiota of female rat

Abstract There are limited data on the effects of a high-fructose diet on the female reproductive system. Although metformin has some functional effects on female fertility, its reproductive outcome on high fructose diet-induced metabolic syndrome is unclear. The aim of the present study is to evalu...

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Main Authors: Mürşide Ayşe Demirel, Esra Şumlu, İbrahim Hanifi Özercan, Kazım Şahin, Mehmet Tuzcu, Veysel Bay, Öznur Ece Durmaz Kurşun, Mecit Orhan Uludağ, Fatma Akar
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
High-fructose diet
Signaling pathways
Metformin
Ovarian tissue
Vaginal microbiota
Online Access:https://doi.org/10.1038/s41598-024-76211-5
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https://doi.org/10.1038/s41598-024-76211-5

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