Dibutyl phthalate promotes central precocious puberty through primordial follicle activation by downregulating BMP15

Dibutyl phthalate promotes central precocious puberty through primordial follicle activation by downregulating BMP15

Dibutyl phthalate (DBP) has been reported to induce central precocious puberty (CPP). However, the mechanism by which DBP accelerates primordial follicle activation and contributes to CPP has not been studied. This study aims to explore the effects of DBP on puberty onset and the role of primordial...

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Bibliographic Details
Main Authors: Yangcheng Yao, Wenjuan Liu, Maoxing Tang, Zhaoyi Wang, Xiqian Zhang, Yufeng Li, Xiaomin Xiao, Fenghua Liu
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Dibutyl phthalate
Central precocious puberty
Primordial follicle
BMP15
AMH
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325008000
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