Linking preclinical models to clinical realities: VEGF/VEGFR inhibitors and thrombotic microangiopathy in cancer therapy

Linking preclinical models to clinical realities: VEGF/VEGFR inhibitors and thrombotic microangiopathy in cancer therapy

Abstract This study examines the link between vascular endothelial growth factor inhibitors (VEGFi) and VEGF receptor inhibitors (VEGFRi) used in treating malignant tumors and the incidence of thrombotic microangiopathy (TMA). Understanding TMA's clinical features and mechanisms is essential fo...

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Bibliographic Details
Main Authors: Aimin Jiang, Zhanzhi Li, Ying Liu, Junyi Shen, Quan Cheng, Anqi Lin, Peng Luo, Linhui Wang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:iMetaOmics
Subjects:
drug‐induced thrombotic microangiopathy
VEGF inhibitors
VEGF receptor inhibitors
Online Access:https://doi.org/10.1002/imo2.70014
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https://doi.org/10.1002/imo2.70014

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