DIA-BERT: pre-trained end-to-end transformer models for enhanced DIA proteomics data analysis

Abstract Data-independent acquisition mass spectrometry (DIA-MS) has become increasingly pivotal in quantitative proteomics. In this study, we present DIA-BERT, a software tool that harnesses a transformer-based pre-trained artificial intelligence (AI) model for analyzing DIA proteomics data. The id...

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Bibliographic Details
Main Authors: Zhiwei Liu, Pu Liu, Yingying Sun, Zongxiang Nie, Xiaofan Zhang, Yuqi Zhang, Yi Chen, Tiannan Guo
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58866-4
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