Natural flavonoids combat cytosolic MRSA by potentiating phagosome acidification

Natural flavonoids combat cytosolic MRSA by potentiating phagosome acidification

Abstract The emergence of multidrug-resistant bacteria (MDR), particularly in cytosolic methicillin-resistant Staphylococcus aureus (MRSA) are causing substantial infections and posing an urgent global threat to public health. The era of antibiotic resistant has hindered the development of antibioti...

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Bibliographic Details
Main Authors: Xiaohui Si, Ruoyi Lv, Ziwen Cai, Zhigang Sun, Wenjing Zhang, Jing Wang, Xiaoye Liu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell Communication and Signaling
Subjects:
Flavonoids
Host-acting antibacterial drugs
Resistant bacteria
Cytosolic MRSA
Phagosome acidification
Online Access:https://doi.org/10.1186/s12964-025-02252-6
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https://doi.org/10.1186/s12964-025-02252-6

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