Comparative Proteome-Wide Abundance Profiling of Yeast Strains Deleted for Cdc48 Adaptors

The yeast ATPase Cdc48 (known as p97/VCP in human cells) plays an important role in the Ubiquitin Proteasome System. VCP is essential for cancer cell proliferation, and its dysregulation has been implicated in several neurodegenerative diseases. Cdc48 functions by extracting ubiquitylated proteins f...

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Bibliographic Details
Main Authors: Valentina Rossio, Joao A. Paulo
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/12/4/31
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