Predicting cortical bone resorption in the mouse tibia under disuse conditions caused by transient muscle paralysis

Abstract Load removal from the load-bearing bone, such as during extended space travel or prolonged bed rest, negatively affects bone health and leads to significant bone loss. However, the underlying principle that relates the bone loss to the lack of physiological loading is poorly understood. Thi...

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Bibliographic Details
Main Authors: Himanshu Shekhar, Sanjay Singh, Jitendra Prasad
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-03588-2
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