In silico modelling of CD8 T cell immune response links genetic regulation to population dynamics

In silico modelling of CD8 T cell immune response links genetic regulation to population dynamics

The CD8 T cell immune response operates at multiple temporal and spatial scales, including all the early complex biochemical and biomechanical processes, up to long term cell population behavior.In order to model this response, we devised a multiscale agent-based approach using Simuscale software. W...

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Bibliographic Details
Main Authors: Thi Nhu Thao Nguyen, Madge Martin, Christophe Arpin, Samuel Bernard, Olivier Gandrillon, Fabien Crauste
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:ImmunoInformatics
Subjects:
Gene regulatory networks
Cell population dynamics
CD8 T cell immune response
Stochastic gene expression
Multiscale modeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2667119024000132
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http://www.sciencedirect.com/science/article/pii/S2667119024000132

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