Clinical, Genetics, and Bioinformatic Characterization of Mutations Affecting an Essential Region of PLS3 in Patients with BMND18

Background. Bone mineral density quantitative trait locus 18 (BMND18, OMIM #300910) is a type of early-onset osteogenesis imperfecta (OI) caused by loss-of-function mutations in the PLS3 gene, which encodes plastin-3, a key protein in the formation of actin bundles throughout the cytoskeleton. Here,...

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Bibliographic Details
Main Authors: Ting Chen, Haiying Wu, Chenxi Zhang, Jiarong Feng, Linqi Chen, Rongrong Xie, Fengyun Wang, Xiuli Chen, Huiting Zhou, Hui Sun, Fei Xiao
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2018/8953217
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