Dynamics of striatal action selection and reinforcement learning

Spiny projection neurons (SPNs) in dorsal striatum are often proposed as a locus of reinforcement learning in the basal ganglia. Here, we identify and resolve a fundamental inconsistency between striatal reinforcement learning models and known SPN synaptic plasticity rules. Direct-pathway (dSPN) and...

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Bibliographic Details
Main Authors: Jack W Lindsey, Jeffrey Markowitz, Winthrop F Gillis, Sandeep R Datta, Ashok Litwin-Kumar
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/101747
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