Coptis japonica Makino ethanol extracts attenuates cancer cachexia induced muscle and fat wasting through inhibition of the STAT3 signaling pathway

Coptis japonica Makino ethanol extracts attenuates cancer cachexia induced muscle and fat wasting through inhibition of the STAT3 signaling pathway

Cancer cachexia is a complex syndrome marked by appetite loss, weakness, fatigue, significant weight loss, and depletion of both adipose and muscle tissue, driven by metabolic and inflammatory alterations caused by tumors. Cachexia is a critical contributor to poor cancer prognosis, often leading to...

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Bibliographic Details
Main Authors: Yo Sep Hwang, Eun Sun Park, Jahyeong Han, Suk Ran Yoon, Jun-Pil Jang, Jong Seok Lim, Seong-Hoon Park, Jun Hong Park, Hee Jun Cho, Hee Gu Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Nutrition
Subjects:
Coptis japonica Makino
cancer cachexia
muscle atrophy
STAT3
IL-6
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1509086/full
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https://www.frontiersin.org/articles/10.3389/fnut.2025.1509086/full

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