Imaging Striatal Microglial Activation in Patients with Parkinson's Disease.

Imaging Striatal Microglial Activation in Patients with Parkinson's Disease.

This study investigated whether the second-generation translocator protein 18kDa (TSPO) radioligand, [18F]-FEPPA, could be used in neurodegenerative parkinsonian disorders as a biomarker for detecting neuroinflammation in the striatum. Neuroinflammation has been implicated as a potential mechanism f...

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Main Authors: Yuko Koshimori, Ji-Hyun Ko, Romina Mizrahi, Pablo Rusjan, Rostom Mabrouk, Mark F Jacobs, Leigh Christopher, Clement Hamani, Anthony E Lang, Alan A Wilson, Sylvain Houle, Antonio P Strafella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0138721&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0138721&type=printable

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