Insulin Predicts Methotrexate Response by Affecting the Transcription of Methotrexate Target Genes in the Treatment-Naive Rheumatoid Arthritis

Methotrexate (MTX), the most common first-line treatment in rheumatoid arthritis, is often insufficient, with no model capable of predicting response. The RA classification criteria, including autoantibodies and inflammation, were applied to 257 patients with newly diagnosed inflammatory arthritis i...

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Bibliographic Details
Main Authors: Victoria M. E. Lundgren, Malin C. Erlandsson, Venkataragavan Chandrasekaran, Sofia Töyrä Silfverswärd, Rille Pullerits, Maria I. Bokarewa
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/13/964
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