Localization of ORC1 During the Cell Cycle in Human Leukemia Cells
The interaction of the origin recognition complex (ORC) with replication origins is a critical parameter in eukaryotic replication initiation. In mammals the ORC remains bound except during mitosis, thus the localization of ORC complexes allows localization of origins. A monoclonal antibody that rec...
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| Main Authors: | Frederick D. Coffman, Mai-Ling Reyes, Monique Brown, W. Clark Lambert, Stanley Cohen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.3233/ACP-2011-0041 |
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