Localization of ORC1 During the Cell Cycle in Human Leukemia Cells

The interaction of the origin recognition complex (ORC) with replication origins is a critical parameter in eukaryotic replication initiation. In mammals the ORC remains bound except during mitosis, thus the localization of ORC complexes allows localization of origins. A monoclonal antibody that rec...

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Bibliographic Details
Main Authors: Frederick D. Coffman, Mai-Ling Reyes, Monique Brown, W. Clark Lambert, Stanley Cohen
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-2011-0041
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