Genetic association analysis between LDL-c lowering drugs and portal hypertension using Mendelian randomization analysis

Abstract Clinical guidelines recommend the use of statins to reduce portal pressure and alleviate portal hypertension (PH). However, there is a lack of population-level studies on the use of non-statin Low-Density Lipoprotein Cholesterol (LDL-c) reduction agents for the treatment of PH. This study u...

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Bibliographic Details
Main Authors: Qing-Ao Xiao, Xiao-Long Li, Lei Qin, Xiao-Lin Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-08153-5
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