High Glucose in Diabetic Hyperglycemia Perturbs Lymphocyte SERCA-Regulated Ca<sup>2+</sup> Stores with Accompanying ER Stress and Signaling Dysfunction

It is well recognized that patients with type 2 diabetes mellitus (T2DM) exhibit significant impairment of immune function resulting in a higher frequency of infections. We hypothesize in this study that a likely contributor to immune dysfunction in T2DM is alteration of T lymphocyte signaling funct...

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Bibliographic Details
Main Authors: Md Nasim Uddin, James L. Graham, Peter J. Havel, Roshanak Rahimian, David W. Thomas
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomolecules
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Online Access:https://www.mdpi.com/2218-273X/15/7/987
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