Metabolite Profiling, Pharmacokinetics, and In Vitro Glucuronidation of Icaritin in Rats by Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry

Icaritin is a naturally bioactive flavonoid with several significant effects. This study aimed to clarify the metabolite profiling, pharmacokinetics, and glucuronidation of icaritin in rats. An ultra-performance liquid chromatography coupled with mass spectrometry (UPLC-MS) assay was developed and v...

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Bibliographic Details
Main Authors: Beibei Zhang, Xiaoli Chen, Rui Zhang, Fangfang Zheng, Shuzhang Du, Xiaojian Zhang
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2017/1073607
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