Anticancer effects of pomegranate-derived peptide PG2 on CDK2 and miRNA-339-5p-mediated apoptosis via extracellular vesicles in acute leukemia

Anticancer effects of pomegranate-derived peptide PG2 on CDK2 and miRNA-339-5p-mediated apoptosis via extracellular vesicles in acute leukemia

Abstract Acute leukemia has rapid onset and severe complications. Anticancer peptides from natural sources have demonstrated efficacy in eliminating various cancers through apoptosis signaling pathways. Additionally, extracellular vesicles containing microRNAs play pivotal roles in promoting tumorig...

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Bibliographic Details
Main Authors: Kantorn Charoensedtasin, Chosita Norkaew, Mashima Naksawat, Wasinee Kheansaard, Sittiruk Roytrakul, Dalina Tanyong
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Pomegranate
MicroRNA
Extracellular vesicles
Apoptosis
Leukemia
Online Access:https://doi.org/10.1038/s41598-024-78082-2
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https://doi.org/10.1038/s41598-024-78082-2

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