Pharmacophore mapping of Angiotensin Converting Enzymes (ACEs): Insight to Binding Site of ACE1 and ACE2

Pharmacophore mapping of Angiotensin Converting Enzymes (ACEs): Insight to Binding Site of ACE1 and ACE2

Angiotensin Converting Enzymes (ACEs) are carboxypeptidase enzymes involved in the renin-angiotensin system (RAS), which catalyze angiotensin I by cleavage of the peptide bond. ACE1 has been known as a target for antihypertensive drugs. Another homolog of ACE1, ACE2 has been popular since 2020 becau...

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Bibliographic Details
Main Authors: Navista Sri Octa Ujiantari, Cintya Nurul Apsari
Format: Article
Language:English
Published: State Islamic University Sunan Kalijaga 2024-10-01
Series:Biology, Medicine & Natural Product Chemistry
Subjects:
pharmacophore mapping
ace1
ace2
active site
homolog protein
Online Access:https://sciencebiology.org/index.php/BIOMEDICH/article/view/541
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https://sciencebiology.org/index.php/BIOMEDICH/article/view/541

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