AvaII senses m6A and inosine sites and enables targeted nanopore direct RNA-sequencing

Nanopore direct RNA-sequencing is the first commercialized method to sequence native RNA directly, thus preserving RNA modifications. With the current technology, sequencing is initiated from the 3′end. While for relatively short polyadenylated RNAs, full coverage is obtained, the 5′end of many long...

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Bibliographic Details
Main Authors: Isabel S. Naarmann-De Vries, Tim Preissendörfer, Julian König, Christoph Dieterich
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1593637/full
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