SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment.

SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment.

The underlying mechanisms leading to antiestrogen resistance in estrogen-receptor α (ER)-positive breast cancer is still poorly understood. The aim of this study was therefore to identify biomarkers and novel treatments for antiestrogen resistant breast cancer. We performed a kinase inhibitor screen...

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Main Authors: Sarah L Larsen, Anne-Vibeke Laenkholm, Anne Katrine Duun-Henriksen, Martin Bak, Anne E Lykkesfeldt, Tove Kirkegaard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118346&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118346&type=printable

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