Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice.

Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice.

Interleukin (IL)-17 is emerging as an important cytokine in vaccine-induced protection against tuberculosis disease in animal models. Here we show that compared to parenteral delivery, BCG delivered mucosally enhances cytokine production, including interferon gamma and IL-17, in the lungs. Furthermo...

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Bibliographic Details
Main Authors: Kristin L Griffiths, Elena Stylianou, Hazel C Poyntz, Gareth J Betts, Helen A Fletcher, Helen McShane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0078312&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0078312&type=printable

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