Genetic diversity and host adaptation of avian H5N1 influenza viruses during human infection

Genetic diversity and host adaptation of avian H5N1 influenza viruses during human infection

The continuing pandemic threat posed by avian influenza A/H5N1 viruses calls for improved insights into their evolution during human infection. We performed whole genome deep sequencing of respiratory specimens from 44 H5N1-infected individuals from Indonesia and found substantial within-host viral...

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Bibliographic Details
Main Authors: Matthijs R.A. Welkers, Hana A. Pawestri, Judy M. Fonville, Ondri D. Sampurno, Maarten Pater, Melle Holwerda, Alvin X. Han, Colin A. Russell, Rienk E. Jeeninga, Vivi Setiawaty, Menno D. de Jong, Dirk Eggink
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Influenza
H5N1
human adaptation
polymerase complex
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1575700
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https://www.tandfonline.com/doi/10.1080/22221751.2019.1575700

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