Single-cell sequencing on PBMCs from patients with HA and HB with inhibitors reveals different immune responses to FVIII and FIX

Abstract: Inhibitors are the most severe complication of replacement therapy in patients with hemophilia. Previous studies, along with our clinical observations, have identified distinct incidence rates and clinical manifestations of factor VIII (FVIII) and FIX inhibitors in patients with severe hem...

Full description

Saved in:
Bibliographic Details
Main Authors: Enhao Li, Zekun Li, Jinzeng Wang, Haoyang Wu, Yilun Xue, Can Lou, Zhenping Chen, Feng Liu, Wenman Wu, Qiulan Ding, Runhui Wu, Xuefeng Wang, Jing Dai
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925002940
Tags: Add Tag
No Tags, Be the first to tag this record!