Management succinate release through SDHA by G protein-coupled receptor 91 signal, TRAP1, and SIRT3 regulation in lung cancer cells by NAR nanoparticles

Background: Cancer cells display oxidative metabolic dysregulation to fulfill their bioenergy requirements. Specifically, efforts were made to regulate the metabolite succinate and its negative effects as an inducer for neoplasm invasion and metastasis. Methods: Binding affinity of naringenin (NAR)...

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Bibliographic Details
Main Authors: Eman M. Ragab, Abeer A. Khamis, Tarek M. Mohamed, Doaa M. El Gamal
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Genetic Engineering and Biotechnology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1687157X25000083
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