Robo1 CAR-NK92 and radiotherapy exert synergistic efficacy in solid tumors

Abstract Background The efficacy of chimeric antigen receptor natural killer (CAR-NK) cells in treating solid tumors is often limited, primarily due to the tumor microenvironment (TME), which hinders the recognition and infiltration of CAR-NK cells. Radiotherapy has been shown to modify the TME, enh...

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Bibliographic Details
Main Authors: Mengdi Wu, Jie He, Jiaxiao Geng, Zhiming Wei, Rong Cheng, Huashun Li, Ligang Xing
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06753-3
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