Prognostic factors of progesterone resistance in symptomatic adenomyosis: impact of lesion localization on treatment outcome of levonorgestrel intrauterine system

Abstract Adenomyosis often causes dysmenorrhea in women of reproductive age. Progestins such as levonorgestrel intrauterine system (LNG-IUS) are often used for treatment, but some patients experience progesterone resistance, showing poor treatment response. However, the clinical characteristics of p...

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Main Authors: Daiki Hiratsuka, Mitsunori Matsuo, Chihiro Ishizawa, Yamato Fukui, Takehiro Hiraoka, Shizu Aikawa, Gentaro Izumi, Miyuki Harada, Osamu Wada-Hiraike, Yutaka Osuga, Yasushi Hirota
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Women's Health
Subjects:
Online Access:https://doi.org/10.1186/s12905-025-03817-w
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