SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis

SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis

Obesity is a prevalent global disease associated with various metabolic disorders. The expansion of white adipose tissue plays a pivotal role in regulating obesity-related metabolic dysfunctions. This study identified serum-defined colon cancer antigen 3 (SDCCAG3) as a novel key modulator of adipocy...

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Bibliographic Details
Main Authors: Fenglei Huo, Chenghang Liu, Xi Wang, Jinzheng Li, Zhifeng Wang, Duanqin Liu, Weipeng Lan, Xingyan Zhu, Jing Lan
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Journal of Lipid Research
Subjects:
adipose tissue
cell signaling
glucose
insulin resistance
metabolic disorders
obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752500032X
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