Identification of compounds targeting porcine reproductive and respiratory syndrome virus nsp3 and evaluation of their antiviral efficacy

Identification of compounds targeting porcine reproductive and respiratory syndrome virus nsp3 and evaluation of their antiviral efficacy

Porcine reproductive and respiratory syndrome virus (PRRSV) is a major threat to global pig farming. Vaccines face challenges like viral recombination and low immunogenicity, highlighting the need for new antivirals. Using molecular docking technology, we screened 200 small molecules interacting wit...

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Bibliographic Details
Main Authors: Zhan He, Zheng Nie, Jiali Liao, Min Liu, Fangfang Li, Binghua Chen, Chunhe Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
Subjects:
PRRSV
Small molecules
Molecular docking
antiviral effect
virulence
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2530176
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https://www.tandfonline.com/doi/10.1080/21505594.2025.2530176

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