Novel brain SPECT imaging unravels abnormal cerebral perfusion in patients with postural orthostatic tachycardia syndrome and cognitive dysfunction

Novel brain SPECT imaging unravels abnormal cerebral perfusion in patients with postural orthostatic tachycardia syndrome and cognitive dysfunction

Abstract Cognitive dysfunction is frequently reported in individuals with postural orthostatic tachycardia syndrome (POTS), possibly resulting from reduced cerebral blood flow (CBF). We used brain SPECT, an accessible imaging modality that has not been systematically evaluated in this patient group....

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Bibliographic Details
Main Authors: Marie-Claire Seeley, Howard O’Brien, Gemma Wilson, Clair Coat, Tess Smith, Kevin Hickson, Reynold Casse, Amanda J. Page, Celine Gallagher, Dennis H. Lau
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Postural orthostatic tachycardia syndrome
Cerebral blood flow
Brain SPECT
Orthostatic intolerance
Post-acute sequelae of COVID-19
Online Access:https://doi.org/10.1038/s41598-025-87748-4
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