Protective efficacy of the pan-fungal vaccine NXT-2 against vulvovaginal candidiasis in a murine model

Abstract Vulvovaginal candidiasis (VVC) is the most common clinical manifestation of candidiasis, affecting 75% of women. Despite high incidence rates, increasing drug resistance, and potential teratogenic effects of current treatments, there are no approved fungal vaccines. Previously, we generated...

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Bibliographic Details
Main Authors: Daniel A. Wychrij, Taylor I. Chapman, Emily Rayens, Whitney Rabacal, Hubertine M. E. Willems, Kwadwo O. Oworae, Brian M. Peters, Karen A. Norris
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-025-01171-4
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