Development and Evaluation of Five-in-One Vaccine Microneedle Array Patch for Diphtheria, Tetanus, Pertussis, Hepatitis B, and <i>Haemophilus influenzae</i> Type b: Immunological Efficacy and Long-Term Stability

Development and Evaluation of Five-in-One Vaccine Microneedle Array Patch for Diphtheria, Tetanus, Pertussis, Hepatitis B, and <i>Haemophilus influenzae</i> Type b: Immunological Efficacy and Long-Term Stability

<b>Background and objectives</b>: The development of a five-in-one vaccine microneedle patch (five-in-one MN patch) aims to address challenges in administering vaccines against Diphtheria (DT), Tetanus (TT), Pertussis (wP), Hepatitis B (HBsAg), and <i>Haemophilus influenzae</i&g...

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Main Authors: In-Jeong Choi, Hye-Ran Cha, Danbi Kwon, Aram Kang, Ji Seok Kim, Jooyoung Kim, Jeong-Eun Choi, Hyeon Woo Chung, Sunghoon Park, Doo Hee Shim, Tae-Hyun Kim, Seung-Ki Baek, Woon-Sung Na, Jae Myun Lee, Jung-Hwan Park
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceutics
Subjects:
combination vaccine
microneedle patch
microneedle array
thermal stability
immunological efficacy
Online Access:https://www.mdpi.com/1999-4923/16/12/1631
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