A polycomb group protein EED epigenetically regulates responses in lipopolysaccharide tolerized macrophages

A polycomb group protein EED epigenetically regulates responses in lipopolysaccharide tolerized macrophages

Abstract Background To avoid exaggerated inflammation, innate immune cells adapt to become hypo-responsive or “tolerance” in response to successive exposure to stimuli, which is a part of innate immune memory. Polycomb repressive complex 2 (PRC2) mediates the transcriptional repression by catalyzing...

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Main Authors: Atsadang Boonmee, Salisa Benjaskulluecha, Patipark Kueanjinda, Benjawan Wongprom, Thitiporn Pattarakankul, Kittitach Sri-Ngern-Ngam, Supawadee Umthong, Junichiro Takano, Haruhiko Koseki, Tanapat Palaga
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Epigenetics & Chromatin
Subjects:
PRC2 complex
Epigenetics
LPS-induced tolerant macrophages
EED
Online Access:https://doi.org/10.1186/s13072-024-00562-6
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https://doi.org/10.1186/s13072-024-00562-6

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