Neural stem cell changes and spatial distribution of AQP4 expression in a fetal goat model of obstructive hydrocephalus

Neural stem cell changes and spatial distribution of AQP4 expression in a fetal goat model of obstructive hydrocephalus

Background: Fetal ventriculomegaly (VM) is a common congenital abnormality with poor outcomes in severe cases, the mechanisms of which include cerebrospinal fluid（CSF）circulation disorders and abnormal neural development. While Aquaporin 4 (AQP4) plays an important role in CSF circulation, its expre...

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Main Authors: Xinting Ji, Qin Zhang, Yuantao Yang, Yan Li, Lihong Li, Shibin Lin, Qi Dong, Zhenling Wan, Julan Wu, Jiadong Bao, Xiaoman Su, Pengzhi Chen, Chenyuan Liu, Weian Song, Zechen Wang, Kang Feng, Xiaoying Li, Shaojiang Zheng, Shuo Gu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:IBRO Neuroscience Reports
Subjects:
Fetal goat
Hydrocephalus
Aquaporin 4 (AQP4)
BioGlue-induced hydrocephalus
Neural stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242125000466
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