Chimeric hemagglutinin and M2 mRNA vaccine for broad influenza subtype protection

Chimeric hemagglutinin and M2 mRNA vaccine for broad influenza subtype protection

Abstract Since multiple and unpredicted influenza viruses cause seasonal epidemics and even high-risk pandemics, developing a universal influenza vaccine is essential to provide broad protection against various influenza subtypes. Combined with the mRNA lipid nanoparticle-encapsulated (mRNA-LNP) vac...

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Main Authors: Dongrong Yi, Qian Liu, Saisai Guo, Quanjie Li, Yongxin Zhang, Ning Li, Qili Zhang, Kai Lv, Ni An, Lu Han, Hua Chen, Yi Wang, Chunyan Chang, Huihan Shao, Jing Wang, Xiaoyu Li, Linlin Bao, Dayan Wang, Guoyang Liao, Chunjian Huang, Weiguo Zhang, Yijie Dong, Yuelong Shu, Shan Cen
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-025-01178-x
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https://doi.org/10.1038/s41541-025-01178-x

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