Parp3 assists muscle function and skeletal muscle differentiation by selectively adjusting H3K27me3 enrichment

Parp3 assists muscle function and skeletal muscle differentiation by selectively adjusting H3K27me3 enrichment

Summary: Poly(ADP-ribose) polymerase 3 (Parp3) is known for its role in DNA repair, mitotic division, and cancer aggressiveness. Still, its physiological roles have yet to be defined. Here, we combined in vivo studies using Parp3-deficient mice with in cellulo studies to explore the involvement of P...

Full description

Saved in:
Bibliographic Details
Main Authors: Zuleyha Yildirim, Aurélia Noll, Kathline Martin-Hernandez, Jean-Christophe Amé, Najat Hanini, Nadia Messaddeq, Isabelle Robert, Bernardo Reina San Martin, Gunn Hildrestrand, Magnar Bjoras, Françoise Dantzer
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:iScience
Subjects:
Molecular mechanism of gene regulation
Epigenetics
Molecular network
Cell biology
Model organism
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225005280
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2589004225005280

Similar Items