Longitudinal study reveals plasma glycans associations with prediabetes/type 2 diabetes in KORA study

Longitudinal study reveals plasma glycans associations with prediabetes/type 2 diabetes in KORA study

Abstract Background Altered plasma N-glycosylation is increasingly recognized as a contributor to metabolic dysregulation. This study aimed to investigate the role of plasma N-glycans in glucose metabolism and the progression from normoglycemia to prediabetes and type 2 diabetes (T2D). Methods We an...

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Main Authors: Jiefei Niu, Elke Rodriguez, Tamara Štambuk, Irena Trbojević-Akmačić, Nikol Mraz, Jochen Seissler, Thomas Skurk, Sabrina Schlesinger, Annette Peters, Gordan Lauc, Christian Gieger, Harald Grallert
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Cardiovascular Diabetology
Subjects:
Plasma N-glycome
Glycomics
Diabetes
Prediabetes
Machine learning
Glycan-QTL
Online Access:https://doi.org/10.1186/s12933-025-02853-y
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https://doi.org/10.1186/s12933-025-02853-y

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