Investigating the protective effect of hydroxylated fullerenes on cognitive function in rats with temporal lobe epilepsy

Investigating the protective effect of hydroxylated fullerenes on cognitive function in rats with temporal lobe epilepsy

Abstract The objective of this study was to explore the protective effects of hydroxy fullerenes (HFs) on cognitive function in rats with temporal lobe epilepsy (TLE) and to elucidate the underlying mechanisms. Eighteen Sprague-Dawley (SD) rats were randomly selected and administered pilocarpine (50...

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Main Authors: Xiaoqing Wang, Shuang Tian, Zhenzhen Qu, Ran Meng, Guangxiao Ni, Min Liu, Huifang Cao
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Temporal lobe epilepsy
Cognitive function
Hydroxylated fullerenes
Postsynaptic density protein-95
Synaptophysin
Online Access:https://doi.org/10.1038/s41598-025-99259-3
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https://doi.org/10.1038/s41598-025-99259-3

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