Genotype inference from aggregated chromatin accessibility data reveals genetic regulatory mechanisms
Abstract Background Understanding the genetic causes underlying variability in chromatin accessibility can shed light on the molecular mechanisms through which genetic variants may affect complex traits. Thousands of ATAC-seq samples have been collected that hold information about chromatin accessib...
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| Main Authors: | Brandon M. Wenz, Yuan He, Nae-Chyun Chen, Joseph K. Pickrell, Jeremiah H. Li, Max F. Dudek, Taibo Li, Rebecca Keener, Benjamin F. Voight, Christopher D. Brown, Alexis Battle |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-025-03538-1 |
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