Hsa-miR-7974 Suppresses Epstein-Barr Virus Reactivation by Directly Targeting <i>BZLF1</i> and <i>BRLF1</i>

Hsa-miR-7974 Suppresses Epstein-Barr Virus Reactivation by Directly Targeting <i>BZLF1</i> and <i>BRLF1</i>

Epstein-Barr virus (EBV) reactivation, a key factor in Epstein-Barr virus (EBV)-associated malignancies, is regulated by specific cellular microRNAs (miRNAs). This study investigated the role of Hsa-miR-7974 (miR-7974) in this process. miRNA sequencing revealed significant downregulation of miR-7974...

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Bibliographic Details
Main Authors: Haotian Li, Hui Wang, Jiao Wang, Xuexin Lu, Jieqiong Zhang, Mingming Wang, Dongbo Yu, Ying Li, Shiwen Wang
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Viruses
Subjects:
Epstein-Barr virus
hsa-miR-7974
lytic cycle
reactivation
Online Access:https://www.mdpi.com/1999-4915/17/5/594
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https://www.mdpi.com/1999-4915/17/5/594

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