Cluster-independent multiscale marker identification in single-cell RNA-seq data using localized marker detector (LMD)

Cluster-independent multiscale marker identification in single-cell RNA-seq data using localized marker detector (LMD)

Abstract Identifying accurate cell markers in single-cell RNA-seq data is crucial for understanding cellular diversity and function. Localized Marker Detector (LMD) is a novel tool to identify “localized genes”—genes exclusively expressed in groups of highly similar cells—thereby characterizing cell...

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Main Authors: Ruiqi Li, Rihao Qu, Fabio Parisi, Francesco Strino, Hainan Lam, Jay S. Stanley, Xiuyuan Cheng, Peggy Myung, Yuval Kluger
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08485-y
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https://doi.org/10.1038/s42003-025-08485-y

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