Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis

Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis

BackgroundHirschsprung-associated enterocolitis (HAEC) is one of the most severe complications in patients with Hirschsprung’s disease (HSCR). Previous research has indicated that acetylcholine (ACH) plays an anti-inflammatory role during inflammation by acting on the α7 nicotinic acetylcholine rece...

Full description

Saved in:
Bibliographic Details
Main Authors: Ziyi Zheng, Lin Lin, Huifang Lin, Jie Zhou, Zhe Wang, Yang Wang, Jianxin Chen, Caimin Lai, Renfu Li, Zhiyong Shen, Ming Zhong, Cheng Xie, Yinjian Chen, Xuechao Zhang, Zhongjie Guo, Rui Dong, Shiwei He, Feng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
Hirschsprung-associated enterocolitis
acetylcholine
tuft cells
macrophages
Hirschsprung’s disease
Ednrb-/- mice
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1559966/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1559966/full

Similar Items