The gut contractile organoid for studying the gut motility regulated by coordinating signals between interstitial cells of Cajal and smooth muscles

The gut contractile organoid for studying the gut motility regulated by coordinating signals between interstitial cells of Cajal and smooth muscles

The gut undergoes peristaltic movements regulated by intricate cellular interactions. How these interactions emerge in the developing gut remains poorly explored due to a lack of model system. We here developed a novel contractile organoid that is derived from the muscle layer of chicken embryonic h...

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Bibliographic Details
Main Authors: Rei Yagasaki, Ryo Nakamura, Yuuki Shikaya, Ryosuke Tadokoro, Ruolin Hao, Zhe Wang, Mototsugu Eiraku, Masafumi Inaba, Yoshiko Takahashi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-08-01
Series:eLife
Subjects:
gut peristalsis
Organoid
oscillation
interstitial cells of cajal
smooth muscle cells
GCaMP
Online Access:https://elifesciences.org/articles/97860
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https://elifesciences.org/articles/97860

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