Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours.

<h4>Background</h4>Disruption of the circadian rhythm is a key feature of bipolar disorder. Variation in genes encoding components of the molecular circadian clock has been associated with increased risk of the disorder in clinical populations. Similarly in animal models, disruption of t...

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Main Authors: Robert Keers, Inti Pedroso, Gerome Breen, Kathy J Aitchison, Patrick M Nolan, Sven Cichon, Markus M Nöthen, Marcella Rietschel, Leonard C Schalkwyk, Cathy Fernandes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0038263&type=printable
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