Quantification of propionic acid from Scutellaria baicalensis roots
Background: Propionic acid is a widely used preservative and has been mainly formed by artificial synthesis or fermentation. In the case of natural products, the presence of propionic acid is viewed as a sign that an additive has been introduced for antimicrobial effects. Methods: In this work, the...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-03-01
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| Series: | Integrative Medicine Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213422016301056 |
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| author | Eunjung Son Ho Kyoung Kim Hyun Sik Kim Mee Ree Kim Dong-Seon Kim |
| author_facet | Eunjung Son Ho Kyoung Kim Hyun Sik Kim Mee Ree Kim Dong-Seon Kim |
| author_sort | Eunjung Son |
| collection | DOAJ |
| description | Background: Propionic acid is a widely used preservative and has been mainly formed by artificial synthesis or fermentation. In the case of natural products, the presence of propionic acid is viewed as a sign that an additive has been introduced for antimicrobial effects.
Methods: In this work, the propionic acid that occurs in Scutellaria baicalensis roots was studied. A quantification method was developed, validated, and showed good linearity, low limit of detection, and limit of quantification values, as well as fine precision and recovery rate. The developed method was applied to the analysis of S. baicalensis roots collected in South Korea and China.
Results: The detection rate for all samples was 94.0%. The average concentration was 0.41 ± 0.24 mg/g from the China sample and 0.76 ± 0.28 mg/g from the Korea sample.
Conclusion: This study is the first to report that propionic acid exists in S. baicalensis roots and also provides a useful ultra performance liquid chromatography analysis method for its quantification. |
| format | Article |
| id | doaj-art-7011c94ecbcf46d78b4b6ce88ee3f8ed |
| institution | OA Journals |
| issn | 2213-4220 |
| language | English |
| publishDate | 2017-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Integrative Medicine Research |
| spelling | doaj-art-7011c94ecbcf46d78b4b6ce88ee3f8ed2025-08-20T02:06:46ZengElsevierIntegrative Medicine Research2213-42202017-03-0161939610.1016/j.imr.2016.11.003Quantification of propionic acid from Scutellaria baicalensis rootsEunjung Son0Ho Kyoung Kim1Hyun Sik Kim2Mee Ree Kim3Dong-Seon Kim4KM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, KoreaKM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, KoreaDivision of Scientific Instrumentation, Korea Basic Science Institute, Cheongju, KoreaDepartment of Food and Nutrition, Chungnam National University, Daejeon, KoreaKM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, KoreaBackground: Propionic acid is a widely used preservative and has been mainly formed by artificial synthesis or fermentation. In the case of natural products, the presence of propionic acid is viewed as a sign that an additive has been introduced for antimicrobial effects. Methods: In this work, the propionic acid that occurs in Scutellaria baicalensis roots was studied. A quantification method was developed, validated, and showed good linearity, low limit of detection, and limit of quantification values, as well as fine precision and recovery rate. The developed method was applied to the analysis of S. baicalensis roots collected in South Korea and China. Results: The detection rate for all samples was 94.0%. The average concentration was 0.41 ± 0.24 mg/g from the China sample and 0.76 ± 0.28 mg/g from the Korea sample. Conclusion: This study is the first to report that propionic acid exists in S. baicalensis roots and also provides a useful ultra performance liquid chromatography analysis method for its quantification.http://www.sciencedirect.com/science/article/pii/S2213422016301056geographical differencespropionic acidquantification analysisScutellaria baicalensisvalidation |
| spellingShingle | Eunjung Son Ho Kyoung Kim Hyun Sik Kim Mee Ree Kim Dong-Seon Kim Quantification of propionic acid from Scutellaria baicalensis roots Integrative Medicine Research geographical differences propionic acid quantification analysis Scutellaria baicalensis validation |
| title | Quantification of propionic acid from Scutellaria baicalensis roots |
| title_full | Quantification of propionic acid from Scutellaria baicalensis roots |
| title_fullStr | Quantification of propionic acid from Scutellaria baicalensis roots |
| title_full_unstemmed | Quantification of propionic acid from Scutellaria baicalensis roots |
| title_short | Quantification of propionic acid from Scutellaria baicalensis roots |
| title_sort | quantification of propionic acid from scutellaria baicalensis roots |
| topic | geographical differences propionic acid quantification analysis Scutellaria baicalensis validation |
| url | http://www.sciencedirect.com/science/article/pii/S2213422016301056 |
| work_keys_str_mv | AT eunjungson quantificationofpropionicacidfromscutellariabaicalensisroots AT hokyoungkim quantificationofpropionicacidfromscutellariabaicalensisroots AT hyunsikkim quantificationofpropionicacidfromscutellariabaicalensisroots AT meereekim quantificationofpropionicacidfromscutellariabaicalensisroots AT dongseonkim quantificationofpropionicacidfromscutellariabaicalensisroots |