A Rfa1-MN-based system reveals new factors involved in the rescue of broken replication forks.

The integrity of the replication forks is essential for an accurate and timely completion of genome duplication. However, little is known about how cells deal with broken replication forks. We have generated in yeast a system based on a chimera of the largest subunit of the ssDNA binding complex RPA...

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Bibliographic Details
Main Authors: Ana Amiama-Roig, Marta Barrientos-Moreno, Esther Cruz-Zambrano, Luz M López-Ruiz, Román González-Prieto, Gabriel Ríos-Orelogio, Félix Prado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011405
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