Molecular Targets of Oxidative Stress: Focus on Nuclear Factor Erythroid 2–Related Factor 2 Function in Leukemia and Other Cancers

Molecular Targets of Oxidative Stress: Focus on Nuclear Factor Erythroid 2–Related Factor 2 Function in Leukemia and Other Cancers

Nuclear factor erythroid 2–related factor 2 (Nrf2) is a transcription factor that plays a central role in regulating cellular responses to oxidative stress. It governs the expression of a broad range of genes involved in antioxidant defense, detoxification, metabolism, and other cytoprotective pathw...

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Bibliographic Details
Main Authors: Syed K. Hasan, Sundarraj Jayakumar, Eliezer Espina Barroso, Anup Jha, Gianfranco Catalano, Santosh K. Sandur, Nelida I. Noguera
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
Nrf2
leukemia
metabolism
ROS
NRF2-inhibitors
lipids
Online Access:https://www.mdpi.com/2073-4409/14/10/713
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