Circ_0000284 Is Involved in Arsenite-Induced Hepatic Insulin Resistance Through Blocking the Plasma Membrane Translocation of GLUT4 in Hepatocytes via IGF2BP2/PPAR-γ

Circ_0000284 Is Involved in Arsenite-Induced Hepatic Insulin Resistance Through Blocking the Plasma Membrane Translocation of GLUT4 in Hepatocytes via IGF2BP2/PPAR-γ

Arsenic exposure can induce liver insulin resistance (IR) and diabetes (DM), but the underlying mechanisms are not yet clear. Circular RNAs (circRNAs) are involved in the regulation of the onset of diabetes, especially in the progression of IR. This study aimed to investigate the role of circRNAs in...

Full description

Saved in:
Bibliographic Details
Main Authors: Shiqing Xu, Zhida Hu, Yujie Wang, Qiyao Zhang, Zhi Wang, Teng Ma, Suhua Wang, Xiaohui Wang, Li Wang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Toxics
Subjects:
arsenic exposure
diabetes mellitus
insulin resistance
circ_0000284
hepatotoxicity
Online Access:https://www.mdpi.com/2305-6304/12/12/883
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2305-6304/12/12/883

Similar Items