Impact of Drp1 Loss on Organelle Interaction, Metabolism, and Inflammation in Mouse Liver

Impact of Drp1 Loss on Organelle Interaction, Metabolism, and Inflammation in Mouse Liver

Dynamin-related protein 1 (Drp1) is a crucial player in mitochondrial fission and liver function. The interactions between mitochondria, endoplasmic reticulum (ER), and lipid droplets (LDs) are fundamental for lipid metabolism. This study utilized liver-specific Drp1 knockout (<i>Drp1</i>...

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Bibliographic Details
Main Authors: Lixiang Wang, Seiji Nomura, Nao Hasuzawa, Sadaki Yokota, Ayako Nagayama, Kenji Ashida, Junjiro Rikitake, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
dynamin-related protein 1
lipid metabolism
organelle interaction
liver inflammation
Online Access:https://www.mdpi.com/2073-4409/14/10/679
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